Publications

All years

2022

The single-cell and spatial transcriptional landscape of human gastrulation and early brain development

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Authors: Zeng B Bo Zeng, Zeyuan Liu, Yufeng Lu, Suijuan Zhong, Shenyue Qin, Luwei Huang, Yang Zeng, Zixiao Li, Hao Dong, Yingchao Shi, Jialei Yang, Yalun Dai, Qiang Ma, Le Sun, Lihong Bian, Dan Han, Youqiao Chen, Xin Qiu, Wei Wang, Oscar Marı´n, Qian Wu, Yongjun Wang, Xiaoqun Wang, Cell Stem Cell. | 2022 [All authors] »

The single-cell and spatial transcriptional landscape of human gastrulation and early brain development

Deciphering the spatial-temporal transcriptional landscape of human hypothalamus development

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Authors: Zhou X Zhou X, Lu Y, Zhao F, Dong J, Ma W, Zhong S, Wang M, Wang B, Zhao Y, Shi Y, Ma Q, Lu T, Zhang J, Wang X, Wu Q, Cell Stem Cell. | 2022 [All authors] »

Deciphering the spatial-temporal transcriptional landscape of human hypothalamus development

2021

Mouse and human share conserved transcriptional programs for interneuron development

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Authors: Shi Y Shi Y, Wang M, Mi D, Lu T, Wang B, Dong H, Zhong S, Chen Y, Sun L, Zhou X, Ma Q, Liu Z, Wang W, Zhang J, Wu Q, Marín O, Wang X, Science. | 2021 [All authors] »

Mouse and human share conserved transcriptional programs for interneuron development

Transcriptomic encoding of sensorimotor transformation in the midbrain

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Authors: Xie Z Xie Z, Wang M, Liu Z, Shang C, Zhang C,Sun L, Gu H, Ran G, Pei Q, Ma Q, Huang M, Zhang J, Lin R, Zhou Y, Zhang J, Zhao M, Luo M, Wu Q, Cao P, Wang X, Elife. | 2021 [All authors] »

Transcriptomic encoding of sensorimotor transformation in the midbrain

Modeling brain development and diseases with human cerebral organoids

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Authors: Shi Y Shi Y, Wu Q, Wang X, Current Opinion in Neurobiology. | 2021 [All authors] »

Modeling brain development and diseases with human cerebral organoids

Interrogation of the microenvironmental landscape in spinal ependymomas reveals dual functions of tumor-associated macrophages

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Authors: Zhang Q Zhang Q, Cheng S, Wang Y, Wang M, Lu Y, Wen Z, Ge Y, Ma Q, Chen Y, Zhang Y, Cao R, Li M, Liu W, Wang B, Wu Q, Jia W, Wang X, Nature Communications. | 2021 [All authors] »

Interrogation of the microenvironmental landscape in spinal ependymomas reveals dual functions of tumor-associated macrophages

2020

Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus.

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Authors: Zhou X Zhou X, Zhong S, Peng H, Liu J, Ding W, Sun L, Ma Q, Liu Z, Chen R, Wu Q, Wang X, Nature Communications. | 2020 [All authors] »

Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus.

Decoding the development of the human hippocampus

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Authors: Zhong S Zhong S, Ding W, Sun L, Lu Y, Dong H, Fan X, Liu Z, Chen R, Zhang S, Ma Q, Tang F, Wu Q, Wang X, Nature. | 2020 [All authors] »

Decoding the development of the human hippocampus

Vascularized human cortical organoids (vOrganoid) model cortical development in vivo

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Authors: Shi Y Shi Y, Sun L, Wang M, Liu J, Zhong S, Li R, Li P, Guo L, Fang A, Chen R, Ge WP, Wu Q, Wang X, Plos Biology. | 2020 [All authors] »

Vascularized human cortical organoids (vOrganoid) model cortical development in vivo

Integrative Analysis of in Vivo Recording with Single-Cell RNA-seq Data Reveals Molecular Properties of Light-Sensitive Neurons in Mouse V1

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Authors: Liu. J Liu. J, Wang M, Sun L, Pan N, Zhang C, Zhang J, Zuo Z, He S, Wu Q, Wang X., Protein Cell. | 2020 [All authors] »

Integrative Analysis of in Vivo Recording with Single-Cell RNA-seq Data Reveals Molecular Properties of Light-Sensitive Neurons in Mouse V1

Visualization and correction of social abnormalities-associated neural ensembles in adult MECP2 duplication mice

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Authors: Sun L Sun L, Chen R, Li L, Yuan B, Song K, Pan N, Cheng T, Chang S, Lin K, He X, Wu Q, Xu F, Qiu Z, Wang X, Science Bulletin. | 2020 [All authors] »

Visualization and correction of social abnormalities-associated neural ensembles in adult MECP2 duplication mice

Single-cell analysis of human retina identifies evolutionarily conserved and species specific mechanisms controlling development

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Authors: Lu Y Lu Y, Shiau F, Yi W, Lu S, Wu Q, Pearson JD, Kallman A, Zhong S, Hoang T, Zuo Z, Zhao F, Zhang M, Tsai N, Zhuo Y, He S, Zhang J, Stein-O'Brien GL, Sherman TD, Duan X, Fertig EJ, Goff LA, Zack DJ, Handa JT, Xue T, Bremner R, Blackshaw S, Wang X, Clark BS, Developmental Cell. | 2020 [All authors] »

Single-cell analysis of human retina identifies evolutionarily conserved and species specific mechanisms controlling development

A single-cell transcriptome atlas of the aging human and macaque retina

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Authors: Yi W Yi W, Lu Y, Zhong S, Zhang M, Sun L, Dong H, Wang M, Wei M, Xie H, Qu H, Peng R, Hong J, Yao Z, Tong Y, Wang W, Ma Q, Liu Z, Ma Y, Li S, Yin C, Liu J, Ma C, Wang X, Wu Q, Xue T, National Science Review. | 2020 [All authors] »

A single-cell transcriptome atlas of the aging human and macaque retina

Abundant self-amplifying intermediate progenitors in the subventricular zone of the Chinese tree shrew neocortex

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Authors: Yin C Yin C, Zhou X, Yao Y, Wang W, Wu Q, Wang X, Cerebral Cortex. | 2020 [All authors] »

Abundant self-amplifying intermediate progenitors in the subventricular zone of the Chinese tree shrew neocortex

Single-cell transcriptome analysis reveals cell lineage specification in temporal spatial patterns in human cortical development.

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Authors: Fan X Fan X, Fu Y, Zhou X, Sun L, Yang M, Wang M, Chen R, Wu Q, Yong J, Dong J, Wen L, Qiao J, Wang X, Tang F, Science Advances. | [All authors] »

Single-cell transcriptome analysis reveals cell lineage specification in temporal spatial patterns in human cortical development.

Loss of the centrosomal protein Cenpj leads to dysfunction of the hypothalamus and obesity in mice.

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Authors: Ding W Ding W, Zhang C, Wang B, Zhou X, Sun L, Zhong S, Liu J, Zhang J, Wang X, Wu Q, . | 2020 [All authors] »

Loss of the centrosomal protein Cenpj leads to dysfunction of the hypothalamus and obesity in mice.

2019

The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice

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Authors: D.L. Tong D.L. Tong, R.G. Chen, Y.L. Lu, W.K. Li, Y.F. Zhang, J.K. Lin, L.J. He, T. Dang, S.F. Shan, X.H. Xu, Y. Zhang, C. Zhang, Y.S. Du, W.H. Zhou, X. Wang, and Z. Qiu, Neurobiol Dis. | 2019 [All authors] »

The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice

Cenpj regulates cilia disassembly and neurogenesis in the developing mouse cortex

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Authors: Ding W Ding W, Wu Q, Sun L, Pan NC, Wang X, Journal of Neuroscience. | 2019 [All authors] »

Cenpj regulates cilia disassembly and neurogenesis in the developing mouse cortex

Morphological and Physiological Characteristics of Ebf2-EGFP-Expressing Cajal-Retzius Cells in Developing Mouse Neocortex

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Authors: Sun L Sun L, Chen R, Bai Y, Li J, Wu Q, Shen Q, Wang X, Cerebral Cortex. | 2019 [All authors] »

Morphological and Physiological Characteristics of Ebf2-EGFP-Expressing Cajal-Retzius Cells in Developing Mouse Neocortex

Early Excitatory Activity-dependent Maturation of Somatostatin Interneurons in Cortical Layer 2/3 of Mice

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Authors: Pan NC Pan NC, Fang A, Shen C, Sun L, Wu Q, Wang X, Cerebral Cortex. | 2019 [All authors] »

Early Excitatory Activity-dependent Maturation of Somatostatin Interneurons in Cortical Layer 2/3 of Mice

2018

A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex

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Authors: Zhong S Zhong S, Zhang S, Fan X, Wu Q, Yan L, Dong J, Zhang H, Li L, Sun L, Pan N, Xu X, Tang F, Zhang J, Qiao J, Wang X, Nature. | 2018 [All authors] »

A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex

Spatial transcriptomic survey of human embryonic cerebral cortex by single-cell RNA-seq analysis

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Authors: Fan X Fan X, Dong J, Zhong S, Wei Y, Wu Q, Yan L, Yong J, Sun L, Wang X, Zhao Y, Wang W, Yan J, Wang X, Qiao J, Tang F, Cell Research. | 2018 [All authors] »

Spatial transcriptomic survey of human embryonic cerebral cortex by single-cell RNA-seq analysis

Vertical Transmission of the Zika Virus Causes Neurological Disorders in Mouse Offspring

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Authors: Shi Y Shi Y, Li S, Wu Q, Sun L, Zhang J, Pan N, Wang Q, Bi Y, An J, Lu X, Gao GF, Wang X., Sci Rep. | 2018 [All authors] »

Vertical Transmission of the Zika Virus Causes Neurological Disorders in Mouse Offspring

2017

The Primate-Specific Gene TMEM14B Marks Outer Radial Glia Cells and Promotes Cortical Expansion and Folding

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Authors: Liu J Liu J, Liu W, Yang L, Wu Q, Zhang H, Fang A, Li L, Xu X, Sun L, Zhang J, Tang F, Wang X, Cell Stem Cell. | 2017 [All authors] »

The Primate-Specific Gene TMEM14B Marks Outer Radial Glia Cells and Promotes Cortical Expansion and Folding

Recapitulating cortical development with organoid culture in vitro and modeling abnormal spindle-like (ASPM related primary) microcephaly disease

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Authors: Li R Li R, Sun L, Fang A, Li P, Wu Q, Wang X, Protein Cell.. | 2017 [All authors] »

Recapitulating cortical development with organoid culture in vitro and modeling abnormal spindle-like (ASPM related primary) microcephaly disease

2016

LSD1 corepressor RCOR2 orchestrates neurogenesis in the developing mouse brain

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Authors: Wang Y Wang Y, Wu Q, Yang P, Wang C, Liu J, Ding W, Liu W, Bai Y, Yang Y, Wang H, Gao S, Wang X, Nature Communications. | 2016 [All authors] »

LSD1 corepressor RCOR2 orchestrates neurogenesis in the developing mouse brain

2015

CRISPR/Cas9-mediated genome engineering of the ferret

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Authors: Kou Z Kou Z, Wu Q, Kou X, Yin C, Wang H, Zuo Z, Zhuo Y, Chen A, Gao S, Wang X, Cell Research. | 2015 [All authors] »

CRISPR/Cas9-mediated genome engineering of the ferret

Before 2015